Ear Drops & Sprays

Sofradex

Sofradex fact card

Sofraxdex contains 2 types of antibiotics and one steroid component, to target bacterial infections and to reduce inflammation

Brand names
Sofradex
Used for
Sofradex is used to treat infection of the ear canal (otitis externa)
Dosage
In the ear: Two drops in the ear three or four times a day
Side effects
Some side effects include: irritation, burning, stinging, itching or swelling.
Warnings
Caution with using this medicine if you're eardrum is perforated. Speak to your doctor first.
Pregnancy
Talk to your doctor before using this medicine if you are pregnant. Safety for use in pregnancy and lactation has not been established.

Sofradex is a combination topical therapy used to treat infections of the ear canal. It consists of a steroid (dexamethasone), to reduce inflammation, an antibiotic (Framycetin) and Gramicidin a mixture of a further 3 antibiotic compounds to tackle localised bacterial infection's.

What is Sofradex used to treat?

Infection's of the ear canal

How does Sofradex work?

Gramicidin disturbs the delicate electrolyte balance of the bacterial cell, Framycetin inhibits bacterial protein synthesis and dexamethasone reduces inflammation - in combination, this treats both the cause of the infection and the painful symptoms that result

How do I take Sofradex?

Child - 2-3 drops in the affected ear, 3-4X daily: do NOT use if perforated ear drum

Adult - 2-3 drops in the affected ear, 3-4X daily: do NOT use if perforated ear drum

Side effects of Sofradex

Rash, itching around the ear canal

Corneal and scleral thinning, migraine

Things to avoid

Avoid concomitant use with anticoagulant medications - increased risk of haemorrhagic events

Sofradex and alcohol

Not contraindicated

Can I take Sofradex when pregnant?

Dexamethasone readily crosses the placenta, manufacturer advises avoid unless benefit outweighs risk

Sofradex and breastfeeding

Manufacturer advises avoid unless benefit outweighs risk